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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
45.15
Human Site:
S1108
Identified Species:
82.78
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S1108
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S1108
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S1108
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Dog
Lupus familis
XP_851777
2404
260682
S1073
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S1109
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Rat
Rattus norvegicus
NP_596872
2444
265618
S1109
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
S1107
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Frog
Xenopus laevis
NP_001088637
2428
264402
S1099
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
G962
Y
E
V
I
W
P
S
G
F
I
C
D
N
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
S1720
L
Y
R
Q
E
P
E
S
V
P
F
R
Y
P
V
Honey Bee
Apis mellifera
XP_001122031
2606
284119
S1309
L
Y
R
Q
D
P
E
S
I
P
F
R
Q
P
V
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
I907
I
P
D
Y
H
E
I
I
K
R
P
M
D
L
E
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
S1317
L
Y
R
Q
N
P
E
S
L
P
F
Q
Q
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
6.6
N.A.
80
93.3
0
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
13.3
N.A.
93.3
100
6.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
8
0
70
0
0
0
0
0
0
8
8
0
0
% D
% Glu:
0
8
0
0
8
8
85
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
85
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
8
8
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
85
0
0
0
0
0
0
0
70
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
93
0
0
0
85
8
0
0
85
0
% P
% Gln:
0
0
0
85
0
0
0
0
0
0
0
8
77
0
0
% Q
% Arg:
0
0
85
0
0
0
0
0
0
8
0
77
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
85
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
85
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
85
0
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _